Open tubular lab-on-column/mass spectrometry for targeted proteomics of nanogram sample amounts.

A novel open tubular nanoproteomic platform featuring accelerated on-line protein digestion and high-resolution nano liquid chromatography mass spectrometry (LC-MS) has been developed. The platform features very narrow open tubular columns, and is hence particularly suited for limited sample amounts...

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Bibliographic Details
Main Authors: Hanne Kolsrud Hustoft, Tore Vehus, Ole Kristian Brandtzaeg, Stefan Krauss, Tyge Greibrokk, Steven Ray Wilson, Elsa Lundanes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0106881