Metagenome sequencing-based strain-level and functional characterization of supragingival microbiome associated with dental caries in children

Metagenome sequencing-based strain-level and functional characterization of supragingival microbiome associated with dental caries in children

Studies of the microbiome associated with dental caries have largely relied on 16S rRNA sequence analysis, which is associated with PCR biases, low taxonomic resolution, and inability to accurately study functions. Here, we employed whole metagenome shotgun sequencing, coupled with high-resolution a...

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Bibliographic Details
Main Authors: Nezar Noor Al-Hebshi, Divyashri Baraniya, Tsute Chen, Jennifer Hill, Sumant Puri, Marisol Tellez, Nur A. Hasan, Rita R. Colwell, Amid Ismail
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Journal of Oral Microbiology
Subjects:
bacteria
dental caries
high-throughput nucleotide sequencing
microbiota
metagenome
Online Access:http://dx.doi.org/10.1080/20002297.2018.1557986

Internet

http://dx.doi.org/10.1080/20002297.2018.1557986

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