The lentiviral integrase binding protein LEDGF/p75 and HIV-1 replication.

Retroviral replication proceeds through a stable proviral DNA intermediate, and numerous host cell factors have been implicated in its formation. In particular, recent results have highlighted an important role for the integrase-interactor lens epithelium-derived growth factor (LEDGF)/p75 in lentivi...

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Bibliographic Details
Main Authors: Alan Engelman, Peter Cherepanov
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-03-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2275779?pdf=render