Mitochondrial fission and mitophagy are independent mechanisms regulating ischemia/reperfusion injury in primary neurons

Abstract Mitochondrial dynamics and mitophagy are constitutive and complex systems that ensure a healthy mitochondrial network through the segregation and subsequent degradation of damaged mitochondria. Disruption of these systems can lead to mitochondrial dysfunction and has been established as a c...

Full description

Bibliographic Details
Main Authors: Anthony R. Anzell, Garrett M. Fogo, Zoya Gurm, Sarita Raghunayakula, Joseph M. Wider, Kathleen J. Maheras, Katlynn J. Emaus, Timothy D. Bryson, Madison Wang, Robert W. Neumar, Karin Przyklenk, Thomas H. Sanderson
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-03752-2