Low Photosensitizer Dose and Early Radiotherapy Enhance Antitumor Immune Response of Photodynamic Therapy-Based Dendritic Cell Vaccination

Low Photosensitizer Dose and Early Radiotherapy Enhance Antitumor Immune Response of Photodynamic Therapy-Based Dendritic Cell Vaccination

Recent studies have highlighted the potential of photodynamic therapy (PDT) to induce immunogenic cell death (ICD). The clinical use of photosensitizers (PS) to stimulate an anticancer immune response, and not to sterilize tumor cells, may however require some optimizations. Here, we examined how th...

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Bibliographic Details
Main Authors: Bastien Doix, Natalia Trempolec, Olivier Riant, Olivier Feron
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Oncology
Subjects:
photodynamic therapy
immunogenic cell death
danger-associated molecular patterns (DAMPs)
radiotherapy
vaccination
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00811/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2019.00811/full

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