Hinged plakin domains provide specialized degrees of articulation in envoplakin, periplakin and desmoplakin.

Envoplakin, periplakin and desmoplakin are cytoskeletal proteins that provide structural integrity within the skin and heart by resisting shear forces. Here we reveal the nature of unique hinges within their plakin domains that provides divergent degrees of flexibility between rigid long and short a...

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Bibliographic Details
Main Authors: Caezar Al-Jassar, Pau Bernadό, Martyn Chidgey, Michael Overduin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3726778?pdf=render