Characterization of structural variation in Tibetans reveals new evidence of high-altitude adaptation and introgression

Abstract Background Structural variation (SV) acts as an essential mutational force shaping the evolution and function of the human genome. However, few studies have examined the role of SVs in high-altitude adaptation and little is known of adaptive introgressed SVs in Tibetans so far. Results Here...

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Bibliographic Details
Main Authors: Cheng Quan, Yuanfeng Li, Xinyi Liu, Yahui Wang, Jie Ping, Yiming Lu, Gangqiao Zhou
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Genome Biology
Subjects:
Online Access:https://doi.org/10.1186/s13059-021-02382-3