CtBP impedes JNK- and Upd/STAT-driven cell fate misspecifications in regenerating Drosophila imaginal discs

CtBP impedes JNK- and Upd/STAT-driven cell fate misspecifications in regenerating Drosophila imaginal discs

Regeneration following tissue damage often necessitates a mechanism for cellular re-programming, so that surviving cells can give rise to all cell types originally found in the damaged tissue. This process, if unchecked, can also generate cell types that are inappropriate for a given location. We co...

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Bibliographic Details
Main Authors: Melanie I Worley, Larissa A Alexander, Iswar K Hariharan
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-01-01
Series:eLife
Subjects:
regeneration
Drosophila
plasticity
tissue repair
transdetermination
Online Access:https://elifesciences.org/articles/30391

Internet

https://elifesciences.org/articles/30391

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