2BC Non-Structural Protein of Enterovirus A71 Interacts with SNARE Proteins to Trigger Autolysosome Formation

2BC Non-Structural Protein of Enterovirus A71 Interacts with SNARE Proteins to Trigger Autolysosome Formation

Viruses have evolved unique strategies to evade or subvert autophagy machinery. Enterovirus A71 (EV-A71) induces autophagy during infection in vitro and in vivo. In this study, we report that EV-A71 triggers autolysosome formation during infection in human rhabdomyosarcoma (RD) cells to facilitate i...

Full description

Bibliographic Details
Main Authors: Jeffrey K. F. Lai, I-Ching Sam, Pauline Verlhac, Joël Baguet, Eeva-Liisa Eskelinen, Mathias Faure, Yoke Fun Chan
Format: Article
Language:English
Published: MDPI AG 2017-07-01
Series:Viruses
Subjects:
picornavirus
enterovirus
enterovirus A71
replication
autophagy
autolysosome
syntaxin-17
synaptosome-associated protein of 29 kDa
SNARE
2BC
Online Access:https://www.mdpi.com/1999-4915/9/7/169

Internet

https://www.mdpi.com/1999-4915/9/7/169

Similar Items