Modeling the Epigenetic Attractors Landscape: Towards a Post-Genomic Mechanistic Understanding of Development

Robust temporal and spatial patterns of cell types emerge in the course of normal development in multicellular organisms. The onset of degenerative diseases may result from altered cell fate decisions that give rise to pathological phenotypes. Complex networks of genetic and non-genetic components u...

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Bibliographic Details
Main Authors: Jose eDavila-Velderrain, Juan Carlos eMartínez-García, Elena R. Alvarez-Buylla
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-04-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00160/full