Transcriptional Regulation of Glucose Metabolism: The Emerging Role of the HMGA1 Chromatin Factor

Transcriptional Regulation of Glucose Metabolism: The Emerging Role of the HMGA1 Chromatin Factor

HMGA1 (high mobility group A1) is a nonhistone architectural chromosomal protein that functions mainly as a dynamic regulator of chromatin structure and gene transcription. As such, HMGA1 is involved in a variety of fundamental cellular processes, including gene expression, epigenetic regulation, ce...

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Bibliographic Details
Main Authors: Eusebio Chiefari, Daniela P. Foti, Riccardo Sgarra, Silvia Pegoraro, Biagio Arcidiacono, Francesco S. Brunetti, Manfredi Greco, Guidalberto Manfioletti, Antonio Brunetti
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Endocrinology
Subjects:
HMGA1
glucose homeostasis
insulin resistance
type 2 diabetes
glucose metabolism
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2018.00357/full

Internet

https://www.frontiersin.org/article/10.3389/fendo.2018.00357/full

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