De novo assembly of bacterial genomes with repetitive DNA regions by dnaasm application
Abstract Background Many organisms, in particular bacteria, contain repetitive DNA fragments called tandem repeats. These structures are restored by DNA assemblers by mapping paired-end tags to unitigs, estimating the distance between them and filling the gap with the specified DNA motif, which coul...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-07-01
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Series: | BMC Bioinformatics |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12859-018-2281-4 |