IL-18/IL-37/IP-10 signalling complex as a potential biomarker for discriminating active and latent TB.

BACKGROUND:Currently, there are serious limitations in the direct diagnosis of active tuberculosis (ATB). We evaluated the levels of the IL-18/IL-37/IP-10 signalling complex proteins in Mycobacterium tuberculosis (M.tb)-specific antigen-stimulated QuantiFERON® Gold In-Tube (QFT) cultures and in seru...

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Bibliographic Details
Main Authors: Sebastian Wawrocki, Michal Seweryn, Grzegorz Kielnierowski, Wieslawa Rudnicka, Marcin Wlodarczyk, Magdalena Druszczynska
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0225556