Plasmodium-specific antibodies block in vivo parasite growth without clearing infected red blood cells.

Plasmodium-specific antibodies block in vivo parasite growth without clearing infected red blood cells.

Plasmodium parasites invade and multiply inside red blood cells (RBC). Through a cycle of maturation, asexual replication, rupture and release of multiple infective merozoites, parasitised RBC (pRBC) can reach very high numbers in vivo, a process that correlates with disease severity in humans and e...

Full description

Bibliographic Details
Main Authors: Jasmin Akter, David S Khoury, Rosemary Aogo, Lianne I M Lansink, Arya SheelaNair, Bryce S Thomas, Pawat Laohamonthonkul, Clara P S Pernold, Matthew W A Dixon, Megan S F Soon, Lily G Fogg, Jessica A Engel, Trish Elliott, Ismail Sebina, Kylie R James, Deborah Cromer, Miles P Davenport, Ashraful Haque
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-02-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC6411214?pdf=render

Internet

http://europepmc.org/articles/PMC6411214?pdf=render

Similar Items