A Novel Heterozygous Variant in F2 Gene in a Chinese Patient With Coronary Thrombosis and Acute Myocardial Infarction Leads to Antithrombin Resistance

A Novel Heterozygous Variant in F2 Gene in a Chinese Patient With Coronary Thrombosis and Acute Myocardial Infarction Leads to Antithrombin Resistance

Thrombophilia refers to a group of conditions where the blood clots more easily than normal. These blood clots can cause problems such as deep vein thrombosis or pulmonary embolism. Most kinds of mutated coagulation factors II (F2) exhibit lower procoagulant activity, but in some cases, a higher coa...

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Bibliographic Details
Main Authors: Yi Tang, Liyang Zhang, Wenlin Xie, Jieyuan Jin, Yujiao Luo, Mingyang Deng, Zhengyu Liu, Hong Wei Pan, Yi Zhang, Zhaofen Zheng, Liang-Liang Fan
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Genetics
Subjects:
F2
coronary thrombosis
acute myocardial infarction
mutation
antithrombin resistance
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2020.00184/full

Internet

https://www.frontiersin.org/article/10.3389/fgene.2020.00184/full

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