Synthesis and Characterization of Celecoxib Derivatives as Possible Anti-Inflammatory, Analgesic, Antioxidant, Anticancer and Anti-HCV Agents

Synthesis and Characterization of Celecoxib Derivatives as Possible Anti-Inflammatory, Analgesic, Antioxidant, Anticancer and Anti-HCV Agents

A series of novel N-(3-substituted aryl/alkyl-4-oxo-1,3-thiazolidin-2-ylidene)-4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamides 2a–e were synthesized by the addition of ethyl a-bromoacetate and anhydrous sodium acetate in dry ethanol to N-(substituted aryl/alkylcarbamoth...

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Bibliographic Details
Main Authors: Amartya Basu, Tanaji T. Talele, Neerja Kaushik-Basu, Azize Şener, Özlem Bingöl Özakpınar, Derya Özsavcı, Özge Çevik, Göknur Aktay, Şule Gürsoy, Sevil Aydın, İnci Coşkun, Ş. Güniz Küçükgüzel
Format: Article
Language:English
Published: MDPI AG 2013-03-01
Series:Molecules
Subjects:
anti-inflammatory
anticancer
celecoxib
hepatitis C NS5B
sulfonylthiourea
Online Access:http://www.mdpi.com/1420-3049/18/3/3595

Internet

http://www.mdpi.com/1420-3049/18/3/3595

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