SimFuse: A Novel Fusion Simulator for RNA Sequencing (RNA-Seq) Data

The performance evaluation of fusion detection algorithms from high-throughput sequencing data crucially relies on the availability of data with known positive and negative cases of gene rearrangements. The use of simulated data circumvents some shortcomings of real data by generation of an unlimite...

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Bibliographic Details
Main Authors: Yuxiang Tan, Yann Tambouret, Stefano Monti
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2015/780519