A DNase from a Fungal Phytopathogen Is a Virulence Factor Likely Deployed as Counter Defense against Host-Secreted Extracellular DNA

A DNase from a Fungal Phytopathogen Is a Virulence Factor Likely Deployed as Counter Defense against Host-Secreted Extracellular DNA

We document that the absence of a single gene encoding a DNase in a fungal plant pathogen results in significantly reduced virulence to a plant host. We compared a wild-type strain of the maize pathogen Cochliobolus heterostrophus and an isogenic mutant lacking a candidate secreted DNase-encoding ge...

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Bibliographic Details
Main Authors: Hee-Jin Park, Weiwei Wang, Gilberto Curlango-Rivera, Zhongguo Xiong, Zeran Lin, David A. Huskey, Martha C. Hawes, Hans D. VanEtten, B. Gillian Turgeon
Format: Article
Language:English
Published: American Society for Microbiology 2019-03-01
Series:mBio
Subjects:
NETs
extracellular DNA
fungi
virulence determinants
Online Access:https://doi.org/10.1128/mBio.02805-18

Internet

https://doi.org/10.1128/mBio.02805-18

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