INSILICO MODELLING ON SOME C14-UREA TETRANDRINE COMPOUNDS AS POTENT ANTI-CANCER AGAINST HUMAN ERYTHROLEUKEMIA (HEL) CELL LINE

INSILICO MODELLING ON SOME C14-UREA TETRANDRINE COMPOUNDS AS POTENT ANTI-CANCER AGAINST HUMAN ERYTHROLEUKEMIA (HEL) CELL LINE

Insulin modeling was performed on 28 C14-urea tetrandrine compounds as inhibitors of leukemic (HEL) cell lines using Quantitative Structure-Activity Relationship (QSAR) method. The structure of the inhibitors was correctly drawn, then geometrically optimized at Density Functional Theory (DFT) level...

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Bibliographic Details
Main Authors: Mustapha Abdullahi, Gideon A. Shallangwa, Tijjani Ali, Adamu Uzairu
Format: Article
Language:English
Published: Universidade Federal de Viçosa (UFV) 2019-03-01
Series:The Journal of Engineering and Exact Sciences
Subjects:
QSAR
Mean Effect
Validation
Descriptors
Model
Y-randomization
Online Access:https://periodicos.ufv.br/ojs/jcec/article/view/3850

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https://periodicos.ufv.br/ojs/jcec/article/view/3850

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