Mathematical modelling reveals unexpected inheritance and variability patterns of cell cycle parameters in mammalian cells.

The cell cycle is the fundamental process of cell populations, it is regulated by environmental cues and by intracellular checkpoints. Cell cycle variability in clonal cell population is caused by stochastic processes such as random partitioning of cellular components to progeny cells at division an...

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Bibliographic Details
Main Authors: Marzena Mura, Céline Feillet, Roberto Bertolusso, Franck Delaunay, Marek Kimmel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-06-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1007054