Glomerular Endothelial Cells as Instigators of Glomerular Sclerotic Diseases

Glomerular Endothelial Cells as Instigators of Glomerular Sclerotic Diseases

Glomerular endothelial cell (GEnC) dysfunction is important in the pathogenesis of glomerular sclerotic diseases, including Focal Segmental Glomerulosclerosis (FSGS) and overt diabetic nephropathy (DN). GEnCs form the first cellular barrier in direct contact with cells and factors circulating in the...

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Bibliographic Details
Main Authors: Marloes Sol, Jan A. A. M. Kamps, Jacob van den Born, Marius C. van den Heuvel, Johan van der Vlag, Guido Krenning, Jan-Luuk Hillebrands
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Pharmacology
Subjects:
Kidney glomerulus (MeSH: D007678)
Glycocalyx (MeSH: D019276)
Endothelial cells (MeSH: D042783)
Podocytes (MeSH: D050199)
Proteinuria (MeSH: D011507)
Diabetic Nephropathy (MeSH: D003928)
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.573557/full

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https://www.frontiersin.org/article/10.3389/fphar.2020.573557/full

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