Impact of superparamagnetic iron oxide nanoparticles on in vitro and in vivo radiosensitisation of cancer cells

Abstract Purpose The recent implementation of MR-Linacs has highlighted theranostic opportunities of contrast agents in both imaging and radiotherapy. There is a lack of data exploring the potential of superparamagnetic iron oxide nanoparticles (SPIONs) as radiosensitisers. Through preclinical 225 k...

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Bibliographic Details
Main Authors: Emily Russell, Victoria Dunne, Ben Russell, Hibaaq Mohamud, Mihaela Ghita, Stephen J. McMahon, Karl T. Butterworth, Giuseppe Schettino, Conor K. McGarry, Kevin M. Prise
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Radiation Oncology
Subjects:
Online Access:https://doi.org/10.1186/s13014-021-01829-y