The Ribosome-Binding Mode of Trichothecene Mycotoxins Rationalizes Their Structure—Activity Relationships

The Ribosome-Binding Mode of Trichothecene Mycotoxins Rationalizes Their Structure—Activity Relationships

Trichothecenes are the most prevalent mycotoxins contaminating cereal grains. Some of them are also considered as the virulence factors of <i>Fusarium</i> head blight disease. However, the mechanism behind the structure-activity relationship for trichothecenes remains unexplained. Fillin...

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Bibliographic Details
Main Authors: Weijun Wang, Yan Zhu, Nadine Abraham, Xiu-Zhen Li, Matthew Kimber, Ting Zhou
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
mycotoxins
trichothecene
mechanism of structure–activity relationships
binding mode
ribosome RNA
binding contacts
Online Access:https://www.mdpi.com/1422-0067/22/4/1604

Internet

https://www.mdpi.com/1422-0067/22/4/1604

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