Elementary Growth Modes provide a molecular description of cellular self-fabrication.

In this paper we try to describe all possible molecular states (phenotypes) for a cell that fabricates itself at a constant rate, given its enzyme kinetics and the stoichiometry of all reactions. For this, we must understand the process of cellular growth: steady-state self-fabrication requires a ce...

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Bibliographic Details
Main Authors: Daan H de Groot, Josephus Hulshof, Bas Teusink, Frank J Bruggeman, Robert Planqué
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1007559