Dexamethasone promotes the endoplasmic reticulum stress response of bone marrow mesenchymal stem cells by activating the PERK‐Nrf2 signaling pathway

Dexamethasone promotes the endoplasmic reticulum stress response of bone marrow mesenchymal stem cells by activating the PERK‐Nrf2 signaling pathway

Abstract The pathogenesis of steroid‐induced avascular necrosis of femoral head (SANFH) is complex, and there is a lack of effective early prevention method. The aim of the present study was to evaluate the effect of dexamethasone (DEX) on the biological behavior of bone marrow mesenchymal stem cell...

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Bibliographic Details
Main Authors: Suoli Cheng, Xueqin Liu, Fan Gong, Xiaoling Ding, Xuebing Zhou, Cuiyun Liu, Fei Zhao, Xiaoliang Li, Jiandang Shi
Format: Article
Language:English
Published: Wiley 2021-05-01
Series:Pharmacology Research & Perspectives
Subjects:
bone marrow mesenchymal stem cells
dexamethasone
endoplasmic reticulum stress
steroid‐induced avascular necrosis of femoral head
Online Access:https://doi.org/10.1002/prp2.791

Internet

https://doi.org/10.1002/prp2.791

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