Increasing CD44<sup>+</sup>/CD24<sup>- </sup>tumor stem cells, and upregulation of COX-2 and HDAC6, as major functions of HER2 in breast tumorigenesis
<p>Abstract</p> <p>Background</p> <p>Cancer cells are believed to arise primarily from stem cells. CD44<sup>+</sup>/CD24<sup>- </sup>have been identified as markers for human breast cancer stem cells. Although, HER2 is a well known breast cancer...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2010-11-01
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| Series: | Molecular Cancer |
| Online Access: | http://www.molecular-cancer.com/content/9/1/288 |