bir1 deletion causes malfunction of the spindle assembly checkpoint and apoptosis in yeast

Cell division in yeast is a highly regulated and well studied event. Various checkpoints are placed throughout the cell cycle to ensure faithful segregation of sister chromatids. Unexpected events, such as DNA damage or oxidative stress, cause the activation of checkpoint(s) and cell cycle arrest. M...

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Bibliographic Details
Main Authors: Qun eRen, Liang-Chun eLiou, Qiuqiang eGao, Xiaoming eBao, Zhaojie eZhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-08-01
Series:Frontiers in Oncology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2012.00093/full