Urea Derivative Catalyzed Enantioselective Hydroxyalkylation of Hydroxyindoles with Isatins

The enantioselective transformations of indoles preferentially take place in the more-reactive azole ring. However, the methods for the enantioselective functionalization of the indole benzene ring are scarce. In this paper, a series of bifunctional (thio)urea derivatives were used to organocatalyze...

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Bibliographic Details
Main Authors: Hao Wu, Liming Wang, Junwei Zhang, Ying Jin
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/24/21/3944