Identification of an iron-responsive subtype in two children diagnosed with relapsing-remitting multiple sclerosis using whole exome sequencing

Background: Multiple sclerosis is a disorder related to demyelination of axons. Iron is an essential cofactor in myelin synthesis. Previously, we described two children (males of mixed ancestry) with relapsing-remitting multiple sclerosis (RRMS) where long-term remission was achieved by regular iron...

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Bibliographic Details
Main Authors: Susan J. van Rensburg, Armand V. Peeters, Ronald van Toorn, Johan Schoeman, Kelebogile E. Moremi, Carel J. van Heerden, Maritha J. Kotze
Format: Article
Language:English
Published: Elsevier 2019-06-01
Series:Molecular Genetics and Metabolism Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2214426919300023