Functional redundancy of HSPA1, HSPA2 and other HSPA proteins in non-small cell lung carcinoma (NSCLC); an implication for NSCLC treatment

Abstract Heat shock proteins (HSPs) are a large group of chaperones considered critical for maintaining cellular proteostasis. Their aberrant expression in tumors can modulate the course of processes defined as hallmarks of cancer. Previously, we showed that both stress-inducible HSPA1 and testis-en...

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Bibliographic Details
Main Authors: Damian Robert Sojka, Agnieszka Gogler-Pigłowska, Natalia Vydra, Alexander Jorge Cortez, Piotr Teodor Filipczak, Zdzisław Krawczyk, Dorota Scieglinska
Format: Article
Language:English
Published: Nature Publishing Group 2019-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-019-50840-7