Succinate Dehydrogenase-Regulated Phosphoenolpyruvate Carboxykinase Sustains Copulation Fitness in Aging C. elegans Males

Summary: Dysregulated metabolism accelerates reduced decision-making and locomotor ability during aging. To identify mechanisms for delaying behavioral decline, we investigated how C. elegans males sustain their copulatory behavior during early to mid-adulthood. We found that in mid-aged males, gluc...

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Bibliographic Details
Main Authors: Jimmy Goncalves, Yufeng Wan, Xiaoyan Guo, Kyoungsun Rha, Brigitte LeBoeuf, Liusuo Zhang, Kerolayne Estler, L. René Garcia
Format: Article
Language:English
Published: Elsevier 2020-04-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220301747