Toll-Like Receptor 2 Release by Macrophages: An Anti-inflammatory Program Induced by Glucocorticoids and Lipopolysaccharide

Toll-Like Receptor 2 Release by Macrophages: An Anti-inflammatory Program Induced by Glucocorticoids and Lipopolysaccharide

Glucocorticoids (GCs) are widely prescribed therapeutics for the treatment of inflammatory diseases, and endogenous GCs play a key role in immune regulation. Toll-like receptors (TLRs) enable innate immune cells, such as macrophages, to recognize a wide variety of microbial ligands, thereby promotin...

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Bibliographic Details
Main Authors: Jessica Hoppstädter, Anna Dembek, Rebecca Linnenberger, Charlotte Dahlem, Ahmad Barghash, Claudia Fecher-Trost, Gregor Fuhrmann, Marcus Koch, Annette Kraegeloh, Hanno Huwer, Alexandra K. Kiemer
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Immunology
Subjects:
innate immunity
corticosteroid
pulmonary macrophage
exosome
microvesicle
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01634/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.01634/full

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