Insights Into GLP-1 and GIP Actions Emerging From Vildagliptin Mechanism Studies in Man

Insights Into GLP-1 and GIP Actions Emerging From Vildagliptin Mechanism Studies in Man

Vildagliptin blocks glucagon like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) inactivation of the meal induced increases in GLP-1 and GIP so that elevated GLP-1 and GIP levels are maintained over 24 h. The primary insulin secretion effect of vildagliptin is to improve th...

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Bibliographic Details
Main Author: James E. Foley
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Endocrinology
Subjects:
β-cell
α-cell
hypoglycemia
lipo-toxicity
weight
type 2 diabetes
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2019.00780/full

Internet

https://www.frontiersin.org/article/10.3389/fendo.2019.00780/full

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