Heterocyclization of polarized system: synthesis, antioxidant and anti-inflammatory 4-(pyridin-3-yl)-6-(thiophen-2-yl) pyrimidine-2-thiol derivatives

Heterocyclization of polarized system: synthesis, antioxidant and anti-inflammatory 4-(pyridin-3-yl)-6-(thiophen-2-yl) pyrimidine-2-thiol derivatives

Abstract Background Chalcones are intent in the daily diet as a favorable chemotherapeutic compound; on the other hand thiophene moiety is present in a large number of bioactive molecules having diverse biological efficiency. Results Our current goal is the synthesis of (E)-1-(pyridin-3-yl)-3-(thiop...

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Bibliographic Details
Main Authors: Wesam S. Shehab, Magda H. Abdellattif, Samar M. Mouneir
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Chemistry Central Journal
Subjects:
Pyrazolopyrimidine
Thiophene
Chalcone
Pyrazol
Pyranone
Anti-inflammatory-antioxidant-cycloxygenase-5-LOX-DPPH
Online Access:http://link.springer.com/article/10.1186/s13065-018-0437-y

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http://link.springer.com/article/10.1186/s13065-018-0437-y

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