The Ras/ERK signaling pathway couples antimicrobial peptides to mediate resistance to dengue virus in Aedes mosquitoes.

Aedes mosquitoes can transmit dengue and several other severe vector-borne viral diseases, thereby influencing millions of people worldwide. Insects primarily control and clear the viral infections via their innate immune systems. Mitogen-Activated Protein Kinases (MAPKs) and antimicrobial peptides...

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Bibliographic Details
Main Authors: Wen-Quan Liu, Si-Qi Chen, Hao-Qiang Bai, Qi-Mei Wei, Sheng-Nan Zhang, Chen Chen, Yi-Han Zhu, Tang-Wei Yi, Xiao-Pu Guo, Si-Yuan Chen, Meng-Jie Yin, Chen-Feng Sun, Shao-Hui Liang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-08-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0008660