SjCRT, a recombinant Schistosoma japonicum calreticulin, induces maturation of dendritic cells and a Th1-polarized immune response in mice

SjCRT, a recombinant Schistosoma japonicum calreticulin, induces maturation of dendritic cells and a Th1-polarized immune response in mice

Abstract Background It is well known that immunization of radiation-attenuated (RA) schistosoma cercariae or schistosomula can induce high levels of protective immunity against schistosoma cercariae reinfection in many animals. Many studies have shown that the Th1 cellular immune response is crucial...

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Bibliographic Details
Main Authors: Lizhen Ma, Dandan Li, Chunxiu Yuan, Xiangqian Zhang, Na Ta, Xiaochao Zhao, Yumei Li, Xingang Feng
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Parasites & Vectors
Subjects:
Calreticulin
Schistosoma japonicum
Dendritic cells
CD4+ T cells
Online Access:http://link.springer.com/article/10.1186/s13071-017-2516-7

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http://link.springer.com/article/10.1186/s13071-017-2516-7

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