Nuclear hormone receptor NHR-49 controls fat consumption and fatty acid composition in C. elegans.

Mammalian nuclear hormone receptors (NHRs), such as liver X receptor, farnesoid X receptor, and peroxisome proliferator-activated receptors (PPARs), precisely control energy metabolism. Consequently, these receptors are important targets for the treatment of metabolic diseases, including diabetes an...

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Bibliographic Details
Main Authors: Marc R Van Gilst, Haralambos Hadjivassiliou, Amber Jolly, Keith R Yamamoto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2005-02-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC547972?pdf=render