Hepatoprotective Effects of Standardized Extracts from an Ancient Italian Apple Variety (Mela Rosa dei Monti Sibillini) against Carbon Tetrachloride (CCl<sub>4</sub>)-Induced Hepatotoxicity in Rats

Hepatoprotective Effects of Standardized Extracts from an Ancient Italian Apple Variety (Mela Rosa dei Monti Sibillini) against Carbon Tetrachloride (CCl<sub>4</sub>)-Induced Hepatotoxicity in Rats

The aim of this research was to examine the effect of the hydroalcoholic extracts from the peel (APE) and pulp (APP) of a traditional apple cultivar from central Italy (Mela Rosa dei Monti Sibillini) on CCl<sub>4</sub>-induced hepatotoxicity in rats. Phytoconstituents were determined by...

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Bibliographic Details
Main Authors: Hasan Yousefi-Manesh, Ahmad Reza Dehpour, Sedighe Ansari-Nasab, Sara Hemmati, Mohammad Amin Sadeghi, Reza Hashemi Shahraki, Samira Shirooie, Seyed Mohammad Nabavi, Joice G. Nkuimi Wandjou, Stefania Sut, Giovanni Caprioli, Stefano Dall’Acqua, Filippo Maggi
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Molecules
Subjects:
CCl4
hepatotoxicity
apple extract
LC-MS
antioxidant
anti-inflammatory
Online Access:https://www.mdpi.com/1420-3049/25/8/1816

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https://www.mdpi.com/1420-3049/25/8/1816

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