Interaction of calcium binding protein S100A16 with myosin-9 promotes cytoskeleton reorganization in renal tubulointerstitial fibrosis

Abstract Renal fibrosis arises by the generation of matrix-producing fibroblasts and myofibroblasts through the epithelial–mesenchymal transition (EMT), a process in which epithelial cells undergo a transition into a fibroblast phenotype. A key feature of the EMT is the reorganization of the cytoske...

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Bibliographic Details
Main Authors: Hui Sun, Anran Zhao, Min Li, Hao Dong, Yifei Sun, Xue Zhang, Qian Zhu, Ashfaq-Ahmad-Shah Bukhari, Changchun Cao, Dongming Su, Yun Liu, Xiubin Liang
Format: Article
Language:English
Published: Nature Publishing Group 2020-02-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-020-2337-z