The ets-related transcription factor GABP directs bidirectional transcription.
Approximately 10% of genes in the human genome are distributed such that their transcription start sites are located less than 1 kb apart on opposite strands. These divergent gene pairs have a single intergenic segment of DNA, which in some cases appears to share regulatory elements, but it is uncle...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2007-11-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC2077898?pdf=render |