The ets-related transcription factor GABP directs bidirectional transcription.

Approximately 10% of genes in the human genome are distributed such that their transcription start sites are located less than 1 kb apart on opposite strands. These divergent gene pairs have a single intergenic segment of DNA, which in some cases appears to share regulatory elements, but it is uncle...

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Bibliographic Details
Main Authors: Patrick J Collins, Yuya Kobayashi, Loan Nguyen, Nathan D Trinklein, Richard M Myers
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-11-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2077898?pdf=render