The MAPK Pathway-Based Drug Therapeutic Targets in Pituitary Adenomas

Mitogen-activated protein kinases (MAPKs) include ERK, p38, and JNK MAPK subfamilies, which are crucial regulators of cellular physiology, cell pathology, and many diseases including cancers. For the MAPK signaling system in pituitary adenomas (PAs), the activation of ERK signaling is generally thou...

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Bibliographic Details
Main Authors: Miaolong Lu, Ya Wang, Xianquan Zhan
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Endocrinology
Subjects:
ERK
p38
JNK
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2019.00330/full