Non-stationary heat transfer in gels applied to biotehnology

• Main Authors: Pokusaev Boris, Vyazmin Andrey, Zakharov Nikolay, Karlov Sergey, Nekrasov Dmitry, Reznik Vyacheslav, Khramtsov Dmitry
• Format: Article
• Language: English
• Published: VINCA Institute of Nuclear Sciences 2017-01-01
• Series: Thermal Science
• Subjects: additive bioprinting; agarose gel; spectroscopy; evaporation; phase transformations; thermophysical coefficients of gel; kinetics of formation; mechanisms of gel aging
• Online Access: http://www.doiserbia.nb.rs/img/doi/0354-9836/2017/0354-98361700125P.pdf
• ISSN: 0354-9836; 2334-7163

Unsteady heat transfer in agarose gels of various concentrations was studied in order to make a breakthrough in the technology of 3-D additive bioprinting. Data on the kinetics of the phase transformation was obtained using spectroscopy as a function of temperature during the formation of agarose hydrogel. The dynamics of aging was investigated for gels of different densities. The time dependence of the structural changes was obtained. Particular attention was paid to the changes in the structure of the gel due to the processes of evaporation of the liquid during the gel formation and during long-term storage. Experiments were performed to determine the dynamics of the temperature fields simultaneously with heat flux measurements during the formation of agarose gels from different initial concentrations. A technique based on experimental data for the computations of the thermophysical coefficients of agarose gels was developed.