Lineage- and developmental stage-specific mechanomodulation of induced pluripotent stem cell differentiation

Lineage- and developmental stage-specific mechanomodulation of induced pluripotent stem cell differentiation

Abstract Background To maximize the translational utility of human induced pluripotent stem cells (iPSCs), the ability to precisely modulate the differentiation of iPSCs to target phenotypes is critical. Although the effects of the physical cell niche on stem cell differentiation are well documented...

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Bibliographic Details
Main Authors: Maricela Maldonado, Rebeccah J. Luu, Gerardo Ico, Alex Ospina, Danielle Myung, Hung Ping Shih, Jin Nam
Format: Article
Language:English
Published: BMC 2017-09-01
Series:Stem Cell Research & Therapy
Subjects:
Induced pluripotent stem cells
Mechanobiology
Differentiation
Substrate stiffness
Online Access:http://link.springer.com/article/10.1186/s13287-017-0667-2

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http://link.springer.com/article/10.1186/s13287-017-0667-2

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