Simulations demonstrate a simple network to be sufficient to control branch point selection, smooth muscle and vasculature formation during lung branching morphogenesis

Summary Proper lung functioning requires not only a correct structure of the conducting airway tree, but also the simultaneous development of smooth muscles and vasculature. Lung branching morphogenesis is strongly stereotyped and involves the recursive use of only three modes of branching. We have...

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Bibliographic Details
Main Authors: Géraldine Cellière, Denis Menshykau, Dagmar Iber
Format: Article
Language:English
Published: The Company of Biologists 2012-06-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/1/8/775