Simulations demonstrate a simple network to be sufficient to control branch point selection, smooth muscle and vasculature formation during lung branching morphogenesis
Summary Proper lung functioning requires not only a correct structure of the conducting airway tree, but also the simultaneous development of smooth muscles and vasculature. Lung branching morphogenesis is strongly stereotyped and involves the recursive use of only three modes of branching. We have...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2012-06-01
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Series: | Biology Open |
Subjects: | |
Online Access: | http://bio.biologists.org/content/1/8/775 |