A Narrative Review on the Role of AMPK on De Novo Lipogenesis in Non-Alcoholic Fatty Liver Disease: Evidence from Human Studies

5′AMP-activated protein kinase (AMPK) is known as metabolic sensor in mammalian cells that becomes activated by an increasing adenosine monophosphate (AMP)/adenosine triphosphate (ATP) ratio. The heterotrimeric AMPK protein comprises three subunits, each of which has multiple phosphorylation sites,...

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Bibliographic Details
Main Authors: Christian von Loeffelholz, Sina M. Coldewey, Andreas L. Birkenfeld
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/10/7/1822