Mesenchymal stem cells activate Notch signaling to induce regulatory dendritic cells in LPS-induced acute lung injury

Mesenchymal stem cells activate Notch signaling to induce regulatory dendritic cells in LPS-induced acute lung injury

Abstract Background Mesenchymal stem cells (MSCs) have been shown to alleviate acute lung injury (ALI) and induce the production of regulatory dendritic cells (DCregs), but the potential link between these two cell types remains unclear. The goal of this study was to investigate the effect and mecha...

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Bibliographic Details
Main Authors: Zhonghua Lu, Shanshan Meng, Wei Chang, Shanwen Fan, Jianfeng Xie, Fengmei Guo, Yi Yang, Haibo Qiu, Ling Liu
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Journal of Translational Medicine
Subjects:
Acute respiratory distress syndrome (ARDS)
Acute lung injury (ALI)
Dendritic cells
Notch
Mesenchymal stem cell (MSC)
Online Access:http://link.springer.com/article/10.1186/s12967-020-02410-z

Internet

http://link.springer.com/article/10.1186/s12967-020-02410-z

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