Examination of potential mechanisms of amyloid-induced defects in neuronal transport

Examination of potential mechanisms of amyloid-induced defects in neuronal transport

Microtubule-based neuronal transport pathways are impaired during the progression of Alzheimer's disease and other neurodegenerative conditions. However, mechanisms leading to defects in transport remain to be determined. We quantified morphological changes in neuronal cells following treatment...

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Bibliographic Details
Main Authors: Sameer B. Shah, Rhiannon Nolan, Emily Davis, Gorazd B. Stokin, Ingrid Niesman, Isabel Canto, Charles Glabe, Lawrence S.B. Goldstein
Format: Article
Language:English
Published: Elsevier 2009-10-01
Series:Neurobiology of Disease
Subjects:
Alzheimer's disease
Amyloid
Axonal transport
Oxidative stress
Aggregation
Morphology
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996109001259

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http://www.sciencedirect.com/science/article/pii/S0969996109001259

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