Feline Infectious Peritonitis Virus Nsp5 Inhibits Type I Interferon Production by Cleaving NEMO at Multiple Sites

Feline Infectious Peritonitis Virus Nsp5 Inhibits Type I Interferon Production by Cleaving NEMO at Multiple Sites

Feline infectious peritonitis (FIP), caused by virulent feline coronavirus, is the leading infectious cause of death in cats. The type I interferon (type I IFN)-mediated immune responses provide host protection from infectious diseases. Several coronaviruses have been reported to evolve diverse stra...

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Bibliographic Details
Main Authors: Si Chen, Jin Tian, Zhijie Li, Hongtao Kang, Jikai Zhang, Jiapei Huang, Hang Yin, Xiaoliang Hu, Liandong Qu
Format: Article
Language:English
Published: MDPI AG 2019-12-01
Series:Viruses
Subjects:
df2
type i ifn
nsp5
nemo
cleavage
Online Access:https://www.mdpi.com/1999-4915/12/1/43

Internet

https://www.mdpi.com/1999-4915/12/1/43

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