Prospective randomised controlled trial of adults with perianal fistulising Crohn’s disease and optimised therapeutic infliximab levels: PROACTIVE trial study protocol

Prospective randomised controlled trial of adults with perianal fistulising Crohn’s disease and optimised therapeutic infliximab levels: PROACTIVE trial study protocol

Introduction Perianal fistulising Crohn’s disease (pfCD) can be somewhat treatment refractory. Higher infliximab trough levels (TLIs) may improve fistula healing rates; however, it remains unclear whether escalating infliximab therapy to meet higher TLI targets using proactive, or routine, therapeut...

Full description

Bibliographic Details
Main Authors: Danny Liew, Ailsa Hart, Niels Vande Casteele, Jordi Rimola, Jane M Andrews, Jakob Begun, Yang Wu, Wei Xuan, Nik Sheng Ding, Bonita Gu, Michael De Gregorio, Joseph Louis Pipicella, William Connell, Basil D’Souza, Ali Gholamrezaei, Graham Radford-Smith, Tom Sutherland, Catherine Toong, Rodney Woods, Watson Ng
Format: Article
Language:English
Published: BMJ Publishing Group 2021-07-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/11/7/e043921.full

Internet

https://bmjopen.bmj.com/content/11/7/e043921.full

Similar Items