Mutations Affecting Potassium Import Restore the Viability of the Escherichia coli DNA Polymerase III holD Mutant.

Mutants lacking the ψ (HolD) subunit of the Escherichia coli DNA Polymerase III holoenzyme (Pol III HE) have poor viability, but a residual growth allows the isolation of spontaneous suppressor mutations that restore ΔholD mutant viability. Here we describe the isolation and characterization of two...

Full description

Bibliographic Details
Main Authors: Adeline Durand, Anurag Kumar Sinha, Cloelia Dard-Dascot, Bénédicte Michel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-06-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4900610?pdf=render